Senator Darline Graham, appointed to fill the vacancy left by the death of her brother, former Senator Lindsey Graham, has indicated to the White House her interest in running for a full Senate term in South Carolina. Graham was appointed after Lindsey Graham's death on July 15, 2026, and was sworn in on July 18, 2026. She has already partnered with Senator Richard Blumenthal to introduce a bill on Russia sanctions.
Former President Donald Trump expressed his support for Graham's potential candidacy, stating he would provide his "complete and total endorsement" if she decides to run. The open primary is generating interest from various candidates within the state GOP, including businessman Mark Lynch and Representatives Nancy Mace, Russell Fry, and Ralph Norman, as well as Lt. Gov. Pamela Evette and former Rep. Mark Sanford.
Trump characterized Graham's appointment as a tribute to her brother and encouraged her to pursue the Senate seat during a recent meeting. A spokesperson for Graham has not yet commented on her potential candidacy, and the White House has not responded to requests for comment.
If Graham enters the race, she will need to balance her Senate responsibilities with the upcoming Republican primary on August 11, 2026, which may lead to a runoff two weeks later if no candidate secures a majority. The Republican nominee will face Democratic candidate Annie Andrews in the general election, who has raised $4 million and is considered a strong contender.