Nanoparticles Deliver mRNA Therapy to Tumors in Cancer Study

Researchers at the University of Adelaide developed 'smart' nanoparticles to deliver mRNA therapy directly to tumor-associated macrophages, aiming to reprogram the immune response against cancer. In a study published in Science Advances, the therapy showed promise in laboratory tests and in mice with aggressive breast cancer, slowing tumor growth and enhancing T cell activity. Further studies are needed to evaluate safety before human trials.